Areas of Activity#

Here you will find all fields of scholarship for this section.
A
  • Adenoviral proteome Go to
  • Adhesion molecules Go to
  • Adhesion Signalling Go to
  • Aging und adaptation of the cardiovascular system Go to
  • Alzheimer’s and Parkinson’s disease Go to
  • Amino acid and phenylpropanoid biosynthesis Go to
  • Anaerobic ammonium oxidation Go to
  • Anaerobic methane oxidation Go to
  • Analysis of genetic diseases Go to
  • Angiogenic growth factors Go to
  • Anopheles/Plasmodium interactions Go to
  • Aorta-gonad-mesonephros region Go to
  • Arabidopsis thaliana Go to
  • Assisted reproduction (in vitro fertilisation) Go to
  • Asymmetric cell division Go to
  • Asymmetric cell divisions Go to
B
  • Basic and clinical aspects of cancer Go to
  • Basic and clinical immunology Go to
  • B cell lineage commitment Go to
  • Behavioural genetics and neurogenetics Go to
  • Biochemical effects of mutations Go to
  • Biochemical genetics of inherited metabolic disease Go to
  • biochemistry & cell biology Go to
  • Bioimaging technology – correlative microscopy Go to
  • Bioinformatics and Computational Biology Go to
  • Biological cells of higher organisms Go to
  • Biological clock of plants and endogenous rhythmicity with non-linear dynamics and spatio-temporal pattern formation of the metabolic cycle of Crassulacean acid Metabolism Go to
  • Biological Engineering Go to
  • Biophysics: Neefjes developed various technologies to measure FRET and FRAP for single cell biochemistry. Go to
  • Biophysics of cardiac and vascular cells Go to
  • Biophysics research of the microtubule cytoskeleton Go to
  • Biosynthesis of alkaloids Go to
  • Biosystems Science Go to
  • Biosythesis of dyes and terpenes in plants Go to
C
  • Caenorhabditis elegans Go to
  • Cancer cell of origin Go to
  • Cancer development Go to
  • Cancer, molecular bases Go to
  • Cancer research in the fields of endocytosis, stem cells and functional genomics Go to
  • Cancer: utilizing biophysics showed conformational changes estrogen receptor and deciphered new resistance mechanism Go to
  • Cardiac disease models Go to
  • Cardiovascular development Go to
  • Cardiovascular development Go to
  • cardiovascular medicine Go to
  • cardiovascular research Go to
  • Cell and Developmental Biology Go to
  • Cell and Developmental Biology Go to
  • cell and developmental biology Go to
  • Cell and Developmental Biology in Drosophila Go to
  • Cell and gene therapy Go to
  • Cell and molecular biology Go to
  • Cell biology: components and regulation of the fission machinery involved in membrane traffic Go to
  • Cell Biology: identified MHC class I and MHC class II cell biology, dynein motor control of vesicles, PI3kinase in MVB biogeneses Go to
  • cell biology, immunology Go to
  • Cell cycle checkpoints Go to
  • cell cycle control Go to
  • Cell cycle control Go to
  • Cell Cycle Control Go to
  • Cell cycle in yeast Go to
  • Cell cycle regulation Go to
  • cell & developmental biology Go to
  • Cell division control Go to
  • Cell fate determination Go to
  • Cell Migration, Cell Proliferation and Signaling Go to
  • cell & molecular biology Go to
  • Cell's cytoskeleton Go to
  • Cell secretion machinery Go to
  • cellular and molecular mechanisms underlying regeneration in salamanders Go to
  • Cellular Biochemistry Go to
  • Cereal plant genomics Go to
  • Characterisation and population distribution of genetic diversity in human populations, especially of the British Isles Go to
  • Characterization of proteins implicated in plant cell-wall synthesis and modification Go to
  • Chemical Biology: developed reciprocal chemical genetics to find host targets controlling bacterial infections and lead structures Go to
  • Chemistry: Neefjes applies chemistry in cell biology. Generated first inhibitors for TAP and for host factor antibiotics Go to
  • Cholesterol dysfunction Go to
  • Chromatin organization in interphase chromosomes Go to
  • Chromatin replication Go to
  • Chromatin research Go to
  • Chromosomal Translocations Go to
  • Chromosome biology Go to
  • Chromosome painting Go to
  • Chromosome pairing and recombination during meiosis Go to
  • Chromosome segregation Go to
  • Chromosome sorting Go to
  • Clinical chemistry (clinical pathology) Go to
  • clinical immunology Go to
  • Clinical Immunology with special focus on autoimmune disease Go to
  • Cloning and reprogramming Go to
  • Codiscoverer of cohesin, a protein complex crucial for faithful chromosome segregation during cell division Go to
  • Colorectal cancers Go to
  • Comparative genome analysis Go to
  • Complex reconstitution experiments of cytoskeletal systems Go to
  • Computational biology and medicine Go to
  • Control of gene expression Go to
  • Ctructural and functional organization of polytene chromosomes Go to
  • Cyclin proteolysis Go to
D
  • Defence mechanisms of arthropods Go to
  • Delineation of immunological mechanisms Go to
  • Developmental and molecular genetics of the nematode Caenorhabditis elegans, with particular reference to nematode-bacterial interactions, innnate immunity and pathogenesis. Go to
  • developmental and regenerative stem cell biology Go to
  • Developmental biology and genetics Go to
  • developmental biology & genetics Go to
  • Developmental biology Go to
  • Developmental biology Go to
  • Developmental biology Go to
  • developmental biology Go to
  • Developmental biology Go to
  • Developmental Biology Go to
  • Developmental Biology Go to
  • Developmental Biology Go to
  • Developmental Biology Go to
  • Developmental biology Go to
  • Developmental biology Go to
  • Developmental biology Go to
  • Developmental biology Go to
  • Developmental biology Go to
  • Developmental Biology Go to
  • Developmental biology Go to
  • Developmental biology Go to
  • Developmental biology Go to
  • Developmental biology Go to
  • Developmental biology Go to
  • Developmental biology Go to
  • developmental biology, mouse genetics Go to
  • developmental genetics Go to
  • Developmental genetics Go to
  • Developmental genetics Go to
  • Developmental genetics Go to
  • Developmental haematopoiesis Go to
  • Developmental morphogenesis Go to
  • Developmental Neuroscience Go to
  • Developmental patterning Go to
  • Developmental patterning (signalling) Go to
  • Developmental signaling Go to
  • Development of B-lymphocytes in greater details Go to
  • Development of cells of the innate and adaptive from stem cells and early progenitors Go to
  • Development of electron microscope tomography Go to
  • Development of mammals Go to
  • Development of structured controlled vocabularies (ontologies) for use in the context of biological databases Go to
  • Development of the blood and immune systems Go to
  • Development of the hematopoietic and vascular systems Go to
  • Development of the nervous system Go to
  • Development of T lymphocytes from pluripotent hemopoietic stem cells Go to
  • Discovering a novel type regulatory RNA - siRNA Go to
  • Discovery of the first inhibitory and of the first activating NK receptors Go to
  • Discovery of the homeobox Go to
  • Discovery of the human immunodeficiency virus (HIV) Go to
  • DNA damage and repair Go to
  • DNA repair and replication Go to
  • Double helix structure of DNA Go to
  • Drosophila development Go to
  • Drosophila genetics and development Go to
  • Drosophila melanogaster Go to
  • Drug target identification: the concepts developed in the laboratory are exploited for the identification of novel targets for drug development Go to
E
  • Early amphibian development Go to
  • Early mammalian development Go to
  • Ecology of anaerobic bacteria and archaea Go to
  • Embryonic development Go to
  • Embryonic development of Vertebrates Go to
  • embryonic morphogenesis Go to
  • Endocytosis/membrane trafficking Go to
  • Endothelial-to-haematopoietic transition Go to
  • Enhancement of the immune response and its relevance to vaccines Go to
  • Epidemiology and Public Health Go to
  • Epigenetic control of gene expression Go to
  • Epigenetic control of gene expression Go to
  • Epigenetic gene control during tissue regeneration Go to
  • Epithelial biology Go to
  • Epithelial-mesenchymal interactions Go to
  • Epithelium morphogenesis Go to
  • Establishment of cell polarity in Drosophila Go to
  • Eukaryotic DNA replication and nuclear protein import Go to
  • Evolutionary biology Go to
  • Evolutionary Biology Go to
  • Experimental avian and mouse embryology Go to
  • Exploring the possible clinical utility of signal transduction antagonists Go to
  • Extravasation of lymphocytes Go to
F
  • Facilitated evolution Go to
  • Field cancerization Go to
  • Firefly luciferase Go to
  • Force generation by dynamic microtubules in-vitro and in-vivo Go to
  • Formation of morphine in mammals and in the human organism Go to
  • Formation of new blood vessels (angiogenesis) Go to
  • Functional genomics Go to
  • Function and regulation of Hox genes Go to
  • Functions of cytokines in vivo Go to
  • Fundamental genetics and biology of colorectal cancer (CRC) and their potential applications Go to
  • Fungal plant pathogens Go to
G
  • Gastrulation and cardiac developmental Go to
  • Gene Expression Regulation, Plant Go to
  • Gene regulation processes Go to
  • Gene regulatory mechanisms Go to
  • Gene Regulatory Networks Go to
  • Genes & Molecular Sequences Go to
  • Gene technology (genetic engineering projects aimed at improving yield stability and food quality of crops) Go to
  • Genetically modified food Go to
  • Genetic aspects of tumor biology Go to
  • Genetic content of interbands Go to
  • Genetic Engineering Go to
  • Genetic engineering Go to
  • Genetic engineering Go to
  • Genetic engineering of plants Go to
  • Genetic fingerprinting Go to
  • Genetic knockout technology Go to
  • Genetic mechanism in cancer and in rare tumors such as Xeroderma Pigmentosus Go to
  • Genetic mechanisms existing in bacteria and bacteriophages Go to
  • Genetic nomenclature Go to
  • Genetic predisposition to disease and cancer Go to
  • Genetics & Genealogy Go to
  • genetics, immunology Go to
  • Genetic susceptibility to Waldenstrom’s macroglobulinemia Go to
  • Genetic underpinnings of cancer Go to
  • Genetic variability of organisms Go to
  • Genome organization and evolution in Drosophila Go to
  • genome organization and stability Go to
  • Germline immortality and telomere function Go to
  • G protein-coupled receptors Go to
  • Growth and cell migration in the zebrafish Go to
H
  • Haematopoietic microenvironment Go to
  • Haematopoietic stem cells Go to
  • Haematopoietic transcription factors Go to
  • Hedgehog signalling Go to
  • Hereditary diseases Go to
  • Heterochromatin formation Go to
  • Higher animal nervous and immune systems Go to
  • High throughput screenings: Neefjes performed various genetic and chemical screens to successfully find new targets and leads Go to
  • Histone methyltransferases Go to
  • Histone modifications Go to
  • Hormonal control of genes activity in the salivary gland cells of Drosophila Go to
  • Host cell gene expression Go to
  • Human pluripotent stem cell biology Go to
  • Huntington's disease Go to
I
  • Idiotypic nature and antibody activity of monoclonal immunoglobulins Go to
  • Imaging by confocal, multiphoton and electron microscopy Go to
  • Immunochemistry, biology and genetics of the complement system Go to
  • immunology, cancer biology Go to
  • Immunology: Mechanisms of control of MHC class I and MHC class II expression, bacterial control phagosomes Go to
  • Immunology of Atherosclerosis with special emphasis on the autoantigenic role of heat shock proteins
  • Immunology of renal and vascular disease Go to
  • Immunopathology, particularly in relation to systemic LE and to multiple sclerosis Go to
  • Infection, Immunology & Inflammation Go to
  • Infections of the central nervous system Go to
  • Inflammatory bowel disease Go to
  • Inflammatory cytokines Go to
  • Informational suppression and gene interaction Go to
  • Innate lymphoid cells Go to
  • Insect innate immunity Go to
  • Insect sting allergy Go to
  • Intravital imaging Go to
  • Invertebrate animals Go to
  • In vivo animal models (mouse, Drosophila melanogaster) Go to
K
L
  • Limb development and regeneration Go to
  • Lipid signalling: the glycerophosphoinositols as phosphoinositide metabolites involved in cell regulation Go to
  • Long non coding RNA Go to
  • Lymphendothelial cells Go to
  • Lymphocyte trafficking Go to
M
  • mammalian genetics Go to
  • Mapping of human genes Go to
  • Mechanism and regulation of non coding RNA function in mammalian cells Go to
  • Mechanism of action of drugs Go to
  • Mechanism of pre-messenger RNA splicing and links to transcription Go to
  • Mechanisms of action of drugs affecting plant growth and development Go to
  • Mechanisms of membrane fission Go to
  • Mechanisms of signal transduction and gene regulation Go to
  • Mechanisms of their transposition Go to
  • Membrane biophysics and proteins. Physiological ecology of plants in the tropics, ecophysiology of photosynthesis Go to
  • Membrane fusion proteins Go to
  • membrane transport Go to
  • Membrane tube formation by molecular motors Go to
  • Metabolism of nitrate Go to
  • Metagenomics of complex microbial communities Go to
  • Microbial ecology of anaerobic micro organism Go to
  • Microbial immunology. Particular topics include microbial subversion of the innate immune response and the immunology of measles Go to
  • Microbial physiology of nitrogen and methane cycle bacteria Go to
  • Microbiology and Immunology Go to
  • Microbiology, Tumour and Cell Biology Go to
  • Microtubules of a Eukaryote cell Go to
  • Mobile genetic elements of higher organisms, Go to
  • Modern mammalian developmental biology Go to
  • Molecular analysis of floral architecture Go to
  • Molecular analysis of neuromuscular and neurological disorders Go to
  • Molecular and cell biology Go to
  • Molecular and cellular mechanisms of neuronal differentiation and diversification Go to
  • Molecular and genetic analysis of development Go to
  • Molecular and pathogenic aspects of viral infections in man and animals Go to
  • Molecular basis of innate immunity Go to
  • Molecular Biology & Genetics Go to
  • Molecular biology of herpes and retroviruses Go to
  • Molecular Biology of the Cell Go to
  • Molecular Biophysics and Biochemistry Go to
  • Molecular Cell Biology Go to
  • Molecular cell biology Go to
  • Molecular Cell Biology Go to
  • Molecular control of heart and skeletal muscle development Go to
  • Molecular cytogenetics Go to
  • Molecular developmental biology Go to
  • Molecular diagnostics Go to
  • Molecular endocrinology Go to
  • Molecular evolution Go to
  • Molecular genetics Go to
  • Molecular genetics Go to
  • Molecular genetics Go to
  • Molecular machinery that drives cell division and controls cell shape Go to
  • Molecular mechanisms Go to
  • Molecular mechanisms in angiogenesis Go to
  • Molecular mechanisms of cellular transformation, with particular emphasis to signal transduction and signal attenuation by growth factor receptors under normal and neoplastic conditions, and in stem cells Go to
  • Molecular mechanisms of evolution of morphological novelties Go to
  • molecular medicine Go to
  • molecular medicine Go to
  • Molecular Medicine: Neefjes applied cell biology and next generation sequencing to find new modes of actions of anticancer drug Go to
  • Molecular networks Go to
  • Molecular networks in leukemia Go to
  • Molecular Neurobiology Go to
  • Molecular oncology Go to
  • Molecular pharmacology Go to
  • Molecular phytopathology Go to
  • molecular plant genetics Go to
  • Molecular population genetics Go to
  • Molecular Sequence Data Go to
  • Molecular Signaling Go to
  • Molecular Virology Go to
  • Monoclonal nature of lymphoid malignancies Go to
  • Morpho-functional organization of intracellular membrane transport in living cells. Go to
  • Morphogenesis of embryos Go to
  • Morphological differentiation Go to
  • Mosquito and comparative genomics Go to
  • Motor system development and function Go to
  • Mouse models of human lymphomas Go to
  • Mucosal immunology Go to
  • Muscle and heart formation Go to
  • Muscle Cell Biology (Skeletal and Cardiac Muscle) Go to
  • Muscle development Go to
  • Muscle gene and cell therapy Go to
  • Muscular dystrophy Go to
  • Musculoskeletal Diseases Go to
  • myogenic cell lineages Go to
  • Myogenic cell lineages Go to
  • Myogenic determination Go to
N
  • Nano-scale measurements of the assembly dynamics of microtubules Go to
  • Natural variation in Arabidopsis and barley Go to
  • Nature and fate of transcription products Go to
  • Neoplastic transformation Go to
  • Nervous system development Go to
  • Neural development (developmental neurobiology) Go to
  • Neurodegenerative diseases Go to
  • neurodegenerative diseases Go to
  • Neurodegenerative diseases Go to
  • Neuroendocrine Signaling Go to
  • Neuronal cell biology Go to
  • Neuronal circuit development, connectivity and function Go to
  • Neuronal circuit tracing by application of viral tools Go to
  • Neuron cytoskeleton Go to
  • Neuroscience & Behavior Go to
  • Neurotransmitter release Go to
  • Non-membrane bound cellular compartments Go to
  • Notch signaling in early T cell development Go to
  • Nuclear transplantation Go to
  • Nucleocytoplasmic Traffic Go to
O
  • Oncogene-induced responses Go to
  • Optical tweezers-based measurements of actin and microtubule forces Go to
  • Organ regeneration Go to
P
  • Pathophysiology of AIDS Go to
  • Pathophysiology of cancer Go to
  • Pathophysiology of nonsecretory and light chain myelomas Go to
  • Pericentric and intercalary heterochromatin Go to
  • Personalised Medicine Go to
  • Photosynthetic carbon assimilation Go to
  • Planar cell polarity Go to
  • Plant and microbial genetics Go to
  • Plant & Animal Science Go to
  • Plant Biotechnology Go to
  • Plant cell biology Go to
  • plant cell biology Go to
  • Plant cell biology Go to
  • Plant cell cycle control Go to
  • Plant cell proliferation Go to
  • plant developmental biology Go to
  • Plant developmental biology Go to
  • plant ecophysiology Go to
  • Plant genetics and physiology Go to
  • Plant hormone signaling Go to
  • plant molecular biology Go to
  • Plant molecular biology Go to
  • Plant systems biology Go to
  • Pluripotent stem cells Go to
  • Polymorphism, Restriction Fragment Length Go to
  • Position effect variegation Go to
  • Positioning of microtubule asters and spindles due to pushing and pulling forces in "artificial cells" Go to
  • Post-traslational modifications: role of endogenous mono-ADP-ribosylation in cell regulation Go to
  • Preimplantational diagnostics Go to
  • Prep1 transcription factor in mammalian development and regulation of Hox activity Go to
  • Presynaptic machinery Go to
  • Progress in animal breeding Go to
  • protein-dna interactions Go to
  • Protein Engineering Go to
  • Protein insertion into the membrane of the endoplasmic reticulum Go to
  • Protein signaling in cells Go to
  • Protein translocation and targeting Go to
  • Proteome organization Go to
  • Proteomic strategies in health and disease Go to
Q
  • Quality control pathways Go to
  • Quantitative genetics Go to
  • Quantitative live imaging Go to
R
  • Reactive Oxygen Species Go to
  • Recombinant DNA research Go to
  • Reconstitution of microtubule end-tracking behavior in-vitro Go to
  • Regulated intramembrane proteolysis Go to
  • Regulation and control systems of the intracellular membrane transport apparatus Go to
  • Regulation of expression of eukaryotic genes Go to
  • Regulation of gene expression Go to
  • Regulation of gene expression Go to
  • Regulation of genetic activity Go to
  • Regulation of the cell cycle Go to
  • Regulation of transcription Go to
  • Regulation of vascular system development Go to
  • Regulatory T cells Go to
  • Relationship between biomedical sciences and society Go to
  • Retro viral oncogenes Go to
  • Retroviruses, including the identification of CD4 as a co-receptor for HIV Go to
  • RNA transport and localised translation Go to
  • Role of lymphocytes in the immune response Go to
  • Role of non coding RNA in gene expression control Go to
  • Role of pericytes (smooth muscle-like cells in microvessels) in vessel integrity Go to
  • Role of Rho and Ras GTPases Go to
  • Role of tau protein in neurodegenerative disorders (tauopathies) like Alzheimer disease Go to
S
  • Selective Autophagy Go to
  • Sensory-motor connectivity Go to
  • Sequence Homology, Amino Acid Go to
  • Signaling Pathways Go to
  • signalling and membrane fission Go to
  • Signal perception and signal transmission Go to
  • Signal transduction Go to
  • Signal transduction Go to
  • Signal transduction Go to
  • Signal transduction Go to
  • Signal transduction Go to
  • Signal transduction Go to
  • Signal transduction Go to
  • Skeletal muscle stem cell commitment and self-renewal Go to
  • Small molecules: synthetic glycerophosphoinositols developed for the treatment of inflammation and "disseminated intravascular coagulation" (DIC); see patents Go to
  • Spatial regulation of V(D)J recombination Go to
  • Spinal cord injury Go to
  • Spinal cord regeneration Go to
  • Spindle assembly checkpoint Go to
  • STAT transcription factors Go to
  • Stem cell commitment in hematopoiesis Go to
  • Stem cell neurobiology and differentiation Go to
  • Stem cell research Go to
  • stem cells and regeneration Go to
  • Stem cells and the regeneration of contractile tissues Go to
  • Stem cell transplantation Go to
  • Strategies which are used to control infectious diseases in developing countries Go to
  • Structural and Molecular Cell Biology Go to
  • Structural Biology Go to
  • Structure and biology of basement membranes Go to
  • Structure and Function of Non-coding RNA-protein Complexes from Eukaryotes Go to
  • Study of mind and higher mental functions Go to
  • Synaptonemal complex Go to
  • Systems Biology: Neefjes has performed integrated screens to generate new biology that was experimentally validated Go to
T
  • Targeted mutagenesis in mice Go to
  • Targeted mutagenesis in the mouse Go to
  • T cell differentiation and tolerance/autoimmunity Go to
  • T-cell malignancies Go to
  • Telomeres and genome stability in ageing Go to
  • the Epstein-Barr virus Go to
  • Theory of X chromosome inactivation Go to
  • Tissue morphogenesis Go to
  • Tissue Regeneration Go to
  • Transcellular migration Go to
  • Transcriptional and replicative activity of polytene chromosomes Go to
  • Transcriptional control of B cell development Go to
  • Transcriptional regulation Go to
  • Transcriptional regulation Go to
  • Transcriptional regulation Go to
  • Transcriptional regulation of urokinase (uPA) gene expression Go to
  • Transcription factor programs regulating neuronal specification Go to
  • Transcription factors controlling B cell immunity Go to
  • Transcription factors Go to
  • Transforming growth factor beta superfamily signalling Go to
  • Translating mechanistic studies on mouse models to normal and diseased humans Go to
  • Translating the knowledge in basic molecular oncology into clinical tools for the amelioration of cancer patient management Go to
  • Transport processes in plants, glands of nectaries and carnivorous plants, roots Go to
  • Tumor angiogenesis Go to
  • Tumor vascularization Go to
  • Tyrosine phosphorylation Go to
U
  • Ubiquitin binding domains Go to
  • Ubiquitin-dependent proteolysis Go to
  • Ubiquitin networks Go to
  • Ubiquitin receptors at the proteasome Go to
V
  • vascular biology and immunology Go to
  • Vascular cell biology Go to
  • Vascular disease modelling Go to
  • Vector-based control of malaria Go to
  • Vertebrate developmental genetics Go to
  • Vertebrate organ formation Go to
  • Vertebrate regeneration Go to
  • Vesicle exocytosis Go to
  • Virulence determinants Go to
W
Y
  • Yeast plasmids and molecular biology Go to
Z

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